Enzyme-Active Retinol Serum

We chose this serum for its strong anti-aging ingredients including a combination of 0.1% retinal, niacinamide, and aloe. It addresses the appearance of fine lines, uneven tone, and rough texture while also supporting hydration and skin comfort.

It’s a worthwhile evening step when you want smoother, more even-looking skin and are ready to build a more thorough skincare routine. Start with a gentle cleanser and finish with the Protocol Renewing Moisturizer.

A good fit for those looking to soften fine lines and improve uneven tone or rough texture with consistent use. It suits those ready to add a targeted treatment to their evening routine. If you are new to retinoids or your skin reacts easily, introduce it gradually and adjust use according to your skin’s comfort. Discontinue or decrease use if irritation occurs.

• Contains 0.1% retinal (retinaldehyde)
• Made with aloe, niacinamide, and glycerin
• Airless, UV-protective packaging using Protocol’s patented oxygen-free bottling technology
• Vegan and cruelty-free
• Designed for evening use, with frequency increased as tolerated

1. In the evening, apply one pump evenly after cleansing. Protocol recommends applying while skin is slightly damp.
2. Allow the serum to absorb for a few minutes, then follow with moisturizer.
3. Start with 1-2 nights per week, then gradually increase as your skin tolerates it.
4. Use broad-spectrum SPF during the day.

If dryness or irritation develops, discontinue use or reduce frequency.

Aloe Barbadensis Leaf Juice, Water, Niacinamide, Cyclodextrin, Caprylic/Capric Triglyceride, Gluconolactone, Carnitine (L), Glycerin, Polysorbate 20, Enzyme-Active Retinol/Retinal/Retinaldehyde, Phenylethyl Resorcinol, Bisabolol (L-alpha), Tocopheryl Acetate (D-alpha), Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Sodium Lactate, Lecithin, Ethanol, Pentylene Glycol, Maltodextrin, Xanthan Gum, Sodium Benzoate